Hippocampus injury from lung barotrauma12/16/2023 ![]() ![]() Apart from this, a damage to the Hippocampus can also cause poor impulse control, hyperactivity, and difficulty with spatial navigation or memory. One symptom of damage to the Hippocampus is Amnesia, or the loss of some portion of the memory. Schizophrenia, is one more condition that may be associated with a damage to the Hippocampus. Even, Encephalitis can cause a damage to the Hippocampus. This small brain structure may also be damaged through chronic seizures in epilepsy. In Alzheimer’s disease, the Hippocampus is one of the first regions of the brain that is affected, leading to the confusion and loss of memory, that is so commonly seen in the early stages of the disease. This could occur, usually during a heart attack, respiratory failure, carbon monoxide poisoning, and sleep apnea.ĭamaged Hippocampus can cause loss of memory and difficulty in establishing new memories. So, periods of oxygen deprivation or Hypoxia, which are not fatal, may nonetheless, cause particular damage to the hippocampus. Epub 2008 Dec 17.The Hippocampus is especially sensitive to the global reductions in the level of oxygen in the body. An analysis of regional microvascular loss and recovery following two grades of fluid percussion trauma: a role for hypoxia-inducible factors in traumatic brain injury. PICK1-mediated GluR2 endocytosis contributes to cellular injury after neuronal trauma. A model of low-level primary blast exposure results in cytoskeletal proteolysis nd chronic functional impairment in the brain in the absence of lung barotrauma. If this happens, it may take several months for the ear to heal completely. Following the work of Dreyfuss et al., which called attention to volume instead of pressure, volutrauma was recognized as the primary driver of VILI. Park E, Gottlieb JJ, Cheung B, Shek PN, Baker AJ. Ear barotrauma can sometimes lead to a ruptured eardrum, also called tympanic membrane perforation. The first recognized form of ventilator-induced lung injury (VILI) was named barotrauma, a word that stresses the role of pressure as a causative agent.Treatment of Traumatic Brain Injury Using Zinc-Finger Protein Gene Therapy Targeting VEGF-A. Siddiq I, Park E, Liu E, Spratt SK, Surosky R, Lee G, Ando D, Giedlin M, Hare GMT, Fehlings MG, Baker AJ.Moreover, it has become clear that applying pressurewhether positive or negativeto the lung can cause damage known as ventilator induced lung injury (VILI). Electrophysiological white matter dysfunction and association with neurobehavioural deficits following low-level primary blast trauma. However, its application has adverse effects including an increased risk of pneumonia, impaired cardiac performance, and neuromuscular problems relating to sedation and muscle relaxants. Bone marrow-derived endothelial progenitor cells protect postischemic axons after traumatic brain injury. A Model of Excitotoxic Brain Injury in Larval Zebrafish: Potential Application for High-Throughput Drug Evaluation to Treat Traumatic Brain Injury. McCutcheon V, Park E, Liu E, Wang Y, Wen XY, Baker AJ. ![]() A novel model of traumatic brain injury in adult zebrafish demonstrates response to injury and treatment comparable with mammalian models. McCutcheon V, Park E, Liu E, SobheBidari P, Tavakkoli J, Wen XY, Baker AJ.Bone marrow-derived endothelial progenitor cell treatment in a model of lateral fluid percussion injury in rats: Evaluation of acute and subacute outcome measures J Neurotrauma. Park E, Park KJ, Liu, E, Jiang R, Zhang J, Baker AJ. ![]()
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